High-frequency developmental abnormalities in p53-deficient mice
نویسندگان
چکیده
منابع مشابه
High-frequency developmental abnormalities in p53-deficient mice
BACKGROUND Several strains of mice carrying null mutations of the tumour suppressor gene p53 have been developed. It has been reported that homozygous mice from all of these strains develop normally to birth, but then succumb rapidly to neoplasia. RESULTS Here, we report that a significant proportion of female p53-/- mice die during embryogenesis or in the period between birth and weaning, be...
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ژورنال
عنوان ژورنال: Current Biology
سال: 1995
ISSN: 0960-9822
DOI: 10.1016/s0960-9822(95)00183-7